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SUMMARY

The zebraONCOfish project has been designed to develop an in vivo platform, aimed to support the cancer chemotherapy selection. Zebrafish shall be used as avatars to aid development of personalized cancer therapies.

This report presents the results on molecular profiling and zebraONCOfish test for each sample included in the study.

In addition, this report details complementary results on experimental procedures used for colon cancer cell lines xenotransplantation into zebrafish embryos, and the evaluation of FDA-approved drugs effectiveness on colon cancer cell lines in vivo. This work has been carried out at the same time as biopsy collection round and the appropriate assays.