zebraONCOfish

This project has received funding from the European Union’s Horizon 2020 research and innovation programme
under grant agreement number 777373

WHAT IS IT?

The idea of analyzing individually the tumor of a patient to determine what combination of drugs will work best is what personalized cancer care is all about.

Thanks to the extensive knowledge acquired by the R&D projects performed in the field by our team for many years and a close collaboration with Hospitals and Cancer Research Institutions, we have identified a remarkable opportunity in ZEBRAONCOFISH project. The ultimate goal of the project presented as ZEBRAONCOFISH is to complete the technical roadmap required to bring to the healthcare market a novel real time in vivo platform for personalized cancer treatment based on the use of zebrafish “avatars” as personalized, living test tubes. Next, we explain briefly the overall project concept &opportunity.

OUR MISSION

ZEBRAONCOFISH’s objective is to use of zebrafish avatars as an in vivo platform to guide therapeutic decisions in actionable cancer patient-directed interventions. For this purpose, these avatars will be created by xenotransplantation of human cancer cells in zebrafish. The chance to carry out a dynamic display of the cancerous process in vivo will offer the unique opportunity to understand the subjacent cancer biology and design tailor-made treatments for each patient.

ZEBRAONCOFISH PROJECT

ZEBRAONCOFISH is based on the evaluation of different types of cancer in zebrafish model. The great advantage of the ZEBRAONCOFISH platform over any test for cancer is that ZEBRAONCOFISH will include the widest range of cancers among those with higher incidence and /or lower survival rates and including hematological malignancies and solid tumors. We will provide a complete molecular profiling of the cancer phenotype using zebrafish avatars platform in the selection of the most effective drug combinations.

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INSTITUTIONS

Navarrabiomed is a biomedical research centre of the Government of Navarre that promotes and facilitates the research of public healthcare professionals. Its location in the heart of the Hospital Complex of Navarre encourages close proximity and collaboration between researchers and professionals working in clinical and healthcare environments.

The Center for Applied Medical Research (CIMA) is the University of Navarra’s biomedical research institute. Its mission is to carry out translational research to a highstandard of excellence, based on novel biological knowledge and aimed at finding therapeutic solutions to patients’ needs.

LATEST NEWS & EVENTS

BIOFIT 2017
A 360° approach to source Life Sciences early-stage innovations

WHAT IS IT?

OUR MISSION

ZEBRAONCOFISH PROJECT

INSTITUTIONS

LATEST NEWS & EVENTS

ZebraONCOfish journey

Zebrafish: Speeding Up the Cancer Drug Discovery Process

7TH PREDICT: TUMOUR MODELS LONDON

X Spanish Drug Discovery Network Meeting (SDDN)